Cairo University

MTPR Journal



Heba Mohamed Fahmy, Ahmed Samir Mohamed, Merna Mostafa Abd El-Hamed, Amira Bahaa El-Din Mustafa, Amena Sayed Elfaky, Esraa Samy Abu Serea
Biophysics Department, Faculty of Science, Cairo University
Vol./Issue: 16 , id: 249

widespread applications in diverse fields such as food packaging industries, wound dressings (artificial skin), tissue engineering, antibacterial agents and carriers in drug delivery/drug release systems especially anticancer drugs. In the present work, we geared up for the first time, Chistosan/starch/gelatin thin films using glycerol as a plasticizer. The current study introduces a comparison between three different concentrations of starch-Chitosan-gelatin blends (12.5:12.5:25) blend I, (15:15:20) blend II and (10:10:30) blend III while using glycerol as a plasticizer in all the blends. The characterizations of thin films were evaluated using X-Ray Diffraction (XRD), Differential Scanning Calorimetry (DSC) and Fourier Transform Infrared Spectroscopy (FTIR). In addition, mechanical properties measurements (tensile strength, elastic modulus and the elongation at break %) were performed. The results of the present study indicated that blend III (10:10:30) showed significant increases in the tensile strength, elastic modulus and the elongation at break% relative to the 2 other blends. These results pointed to better mechanical properties emphasized by blend III. XRD demonstrated the crystalline structure in the prepared thin films. In addition, FTIR showed that the three materials used (Chitosan, starch and gelatin) were well cross linked together which resulted in a homogeneous mixture. In conclusion, The present study presented a flexible blend (blend III) made of Stach/Chistosan/ gelatin with the ratios (10:10:30) with good mechanical properties that can be applied in various applications. Further studies are needed to test the engineered thin films created in the present work in diverse applications such as food packaging, skin compensators or others.